A Secret Weapon For ceesdekker.net
A Secret Weapon For ceesdekker.net
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1996, very first mesoscopic demand density waves devices; and 1st electrical measurements on a single steel nanocluster involving nanoelectrodes
‘It absolutely was simply just a make any difference of finding up a e book on mobile biology and beginning to examine. I had come from a environment of extremely-superior vacuums, cryostats and quantum phenomena, and now I used to be Performing at area temperature with molecular biology kits.
Deposition and atomic drive microscopy of individual phthalocyanine polymers between nanofabricated electrodes
2015, discovery that condensin is a really versatile protein framework; and 1st detection of DNA knots utilizing nanopores
SMC complexes can pass physical roadblocks larger than their ring sizing, indicating a nontopological mechanism for DNA loop extrusion
We use nanofabricated microfluidic structures to sample spatial boundaries for microbes and biomimetic vesicles with reconstituted protein networks which evaluate the basic position of spatial confinement for the molecular and mobile stage. Our initiatives include things like the next:
Illustration (1) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is shown in gray, the rim of the pore is highlighted in purple, along with ceesdekker.net a 3D rendering of your movement in the DNA rod is exhibited.
‘Of course, I recognize individuals were stunned at time. At the conclusion of the nineties, when I was in my forties, I used to be Professor of Molecular Electronics and I've to confess that it experienced become a little bit bored, I didn’t discover Substantially any more. The sector went extra into the application facet, how you can combine nanotubes into Digital circuits.
At this time, we also recognized that it should be feasible to make use of a single semiconducting carbon nanotube to make a transistor — and we established out to really make it. We stretched particular person semiconducting nanotubes throughout metallic electrodes and employed the underlying silicon substrate as a gate electrode, establishing The essential 3-terminal format of a industry-outcome transistor (Fig.
Considering that 2000 he moved to single-molecule biophysics and nanobiology, with exploration from scientific studies of DNA loop extrusion and supercoiling to DNA translocation via nanopores. Additional not too long ago his research has centered on studying chromatin framework and cell division with microorganisms on chip, whilst he is likewise trying to finally Construct artificial cells from the bottom up.
Mother nature Physics thanks the nameless reviewers for their contribution into the peer critique of this do the job.
Visualization of unstained DNA nanostructures with State-of-the-art in-focus transmission electron microscopy methods
2004, discovery of recent physics in translocation of DNA by way of nanopores; initial experimental analyze of ions conduction in nanofluidic channels; 1st electrochemistry with person one-wall carbon nanotubes; STM detection and control of phonons in carbon nanotubes; to start with electrical docking of microtubules on kinesin-coated nanostructures; 1st biophysics characterization from the mechanical Attributes of double-stranded RNA; and very first single-molecule examine of DNA translocation by a restriction-modification enzyme.